Is oral-fluid (mouth-swab) drug testing allowed under DOT now? 

Oral-fluid testing is authorized under 49 CFR Part 40, but it is not yet usable. It only becomes “available” when at least two HHS-certified oral-fluid laboratories, a qualified oral-fluid collector, and a conforming collection device all exist. As of mid-2026, there are no HHS-certified oral-fluid laboratories, so urine remains the only usable method. 

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